How long does Vyvanse stay in your system?

You might have heard about this ingredient before and wonder what the effects it can bring to your system. If you have worked in the medical field, this is not a strange thing to you, however, to those who are not familiar with medical terms, Vyvanse is a medicinal drug using to treat ADHD which is called Attention Deficit Hyperactivity Disorder). It is the label name of lisdexamfetamine that is a pharmaceutical ingredient classified as a psychostimulant. Together with Adderall, Vyvanse is adopted to treat BED (aka Binge Eating Disorder) and other mental problems.

What are inside Vyvanse?

Lisdexamfetamine is the only one ingredient found in Vyvanse, and it is also the only available source of Vyvanse. Therefore, you can treat them as the same thing even though their names are different. A common question has arisen among various people is that whether Vyvanse is an amphetamine. The answer to the question is yes as lisdexamfetamine is an amphetamine salt. Therefore, after taking the drug, your body might metabolize and transform these substances into amphetamine. Also, the mechanism applies to Adderall which consists of four distinct kinds of amphetamine salts. They seem to impose similar effects, however, unlike Vyvanse, Adderall might impose a possible side effect that Vyvanse.

 Differences between Adderall and Vyvanse

In several studies, they compare the effectiveness of Adderall and Vyvanse to the CNS which is also known as Central Nervous System. While Vyvanse has verified itself to be as precious as Adderall, it has fewer side effects than Adderall. The mystery of that outcome might lie in the ingredient they use to produce Adderall and Vyvanse.

While Vyvanse consists only one amphetamine salt which is lisdexamfetamine, Adderall consists four different types of salts. As a result, the chemical resonance in the four distinct kinds of salts has imposed a higher capability of the drug. However, it also raises that adverse side effects as well.

Since they are both amphetamine salts, they will provide you same effects of the amphetamine including the possibilities for drug abuse. Vyvanse requires converting into its active form to affect while Adderall directly imposes consequences on the CNS. Especially, Vyvanse has less potential for the addiction. Moreover, in several neurologists’ concepts, Vyvanse can be considered as the successor of Adderall thank its equivalent outcomes on CNS with fewer side effects.

How does Vyvanse work?

The basic model of ADHD is tied to neurotransmitter system’s functional impairment. No sooner has Vyvanse or lisdexamfetamine gotten into your body, under catalyzation by the enzymes on the red blood cells than it is transformed into L – lysine as well as dextroamphetamine which are Vyvanse’s active forms.

The compounds can rise the central neurotransmitter systems activities by activating the release of norepinephrine and dopamine at the neutrons’ terminal. The released compounds are neurotransmitters. Thus, they can contribute to consciousness as well as enhance concentration, effort, and motivation.

Moreover, a large-scale study has shown that about 80% of patients with ADHD have significant improvement after being prescribed with Vyvanse. The study has made itself devote to the hypothesis of the Vyvanse action’s mechanism.

How long does Vyvanse take to work?

The Vyvanse might take a long time to degrade and be absorbed after we have made it. In several studies conducted to understand Vyvanse pharmacokinetics, they have provided us essential information about the time the drug took to work. 3 hours and 7 hours after taking the medication, the release and extended release of different lisdexamfetamine will reach the peak plasma concentrations.

Discontinuation of Vyvanse

Those who are taking Vyvanse might feel discomfort after stopping adopting the drug. Even though the medication is legally prescribed, it is still an amphetamine which implies that it can cause addiction range from mild one to a severe one. The discomfort might develop from lethargy, brain fog with withdrawal symptoms can be seen such as sweating, irritability, lack of appetite to even hypersensitivity. Such effects might cause you wonder whether the drug remains in your system. Thus to know how long the Vyvanse takes to be removed from your system, it is vital to understand Vyvanse’s half-life time and the place it stays in your body.

How long does Vyvanse stay in your system?

Before going to answer the main question of the article, it is essential to know how the system works. The drug might appear anywhere in your body after being taken as the bloodstream delivers it. However, because it is mostly carried to other parts of your body via the bloodstream, the substances will mostly stay in the saliva, blood, hair and urine system. According to this characteristic, scientists also provide Vyvanse test respectively to answer the question more precisely.

Former information has claimed that Vyvanse can be metabolized to L-lysine and dextroamphetamine. While the dextroamphetamine has the pharmaceutical effects on CNS, L-lysine is an acid amine and can be absorbed in the biosynthesis of protein. Thus Vyvanse’s half-life elimination is the half-life elimination of dextroamphetamine.

The time might vary from nine to eleven hours which implies that the drug will vanish gradually. However, it will stay in the system for two days to 2 and a half days before being eliminated entirely. Including the time for the system to absorb as well as metabolize Vyvanse, we can say that the maximum time Vyvanse take to last in your body is about three days.

The studies conducted to understand about half-life time expulsion of the Vyvanse are also used in Vyvanse test. For example, Vyvanse lasts in the urine system for about three days, in a hair test for one month, in the blood for 8 to 24 hours and saliva for about two days. As Vyvanse is an amphetamine ingredient, its degradation is affected by pH level (an index shows how basic or acidic the liquid is).

Vyvanse drug test

Also known as Vyvanse drug screening, toxicology urine screening or AMP, however, Vyvanse drug test is most commonly known as urine screening test since it is convenient, low – cost and most importantly, it imposes no threaten or complication and the time the drug will stay in the urine is sufficient to determine. With the information provided above, it can be easily guessed that for those who have taken Vyvanse for the last three days, the result will be positive and the lab will confirm that.

For those who take a blood test, the time Vyvanse stays in their system will be less than those who take urine system’s test. Moreover, it also requires blood sample which will expose the patient to many types of risk. For such reasons, it is not highly recommended. Similar to a urine test, the result will be positive within 24 hours after the Vyvanse being taken.

Even though the usual time for Vyvanse clearance is about three days, different factors might affect the outcome. Most common factors that should be considered are individual factors, dosage, drug interactions and the frequency of use.

Vyvanse if widely used without appropriate awareness and knowledge about the drug is dangerous. Hopefully, the information in the article has helped you to know how to use the Vyvanse medication. However, for proper use and the dosage of each, we highly recommend you to visit your doctor and ask for advice.

All the information is reviewed and accumulated from various trustworthy and scientific – based sources. If you find this article helpful, leave us like and share, we are glad to expose this good knowledge to as many people as possible.




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